Kutheni le nto isifo se-Alzheimer sichaphazela abafazi abaninzi kunamadoda?

Kukho into eyothusayo, encinci eyaziwayo malunga nesifo se-Alzheimer's (AD), isifo se-neurodeergenerative esichaphazela ama-5.8 ezigidi zaseMelika-sichaphazela ngokungafaniyo abasetyhini. Isibini kwisithathu kwabo bafunyaniswe benesifo i-Alzheimer e-US ngabasetyhini, ngokutsho kwengxelo ye-Alzheimer's Association. Izazinzulu azazi ukuba kutheni.

I-Movement ye-Alzheimer's Movement (WAM), engenzi nzuzo esekwe nguMaria Shriver, iphambili ekuthatheni inyathelo lokunceda ekufumaneni izisombululo. Ugqirha Sanjay Gupta, u-Emmy Award ophumelele imbasa kwezonyango, wajoyina i-Shriver kwi-WAM Research Awards Summit eyabanjwa nge-11 kaFebruwari 2021, ukuhlonipha abo bafumana i-500,000 yeedola ekunikeni inkxaso-mali yophando olwenziwa sisifo se-Alzheimer's.

Intatheli ephumelele amabhaso ka-Emmy, umbhali othengisa kakhulu, kunye nowayesakuba ngumfazi wokuqala waseCalifornia, uMaria Shriver uyakwazi ukutshatyalaliswa kwe-Alzheimer's. Utata wakhe ongasekhoyo, uSargent Shriver, kwafunyaniswa ukuba unesifo sika-Alzheimer ngo-2003. Wasungula i-WAM ngenjongo yokuxhasa uphando olwenziwa ngabasetyhini kumaziko ezenzululwazi kwilizwe liphela, ukulungiselela ukujongana neemfuno ezithile zabasetyhini, kubandakanya nabasetyhini bebala , ukunceda ukunciphisa umngcipheko wesifo sika-Alzheimer.

"Kulo nyaka sigxile kumandla ophando ukutshintsha umkhondo wempilo yengqondo yabasetyhini ngonaphakade," utshilo uShriver kwi "The Brain future" kwi Psychology Today.

UGupta yi-neurosurgeon kunye nombhali wencwadi entsha Gcina ubukhali: Yakha uBongo obungcono nangaliphi na ixesha enikezela ukuqonda kwesayensi ngendlela yokuphakamisa nokukhusela ukusebenza kwengqondo kunye nokugcina impilo yokuqonda. Xa wayekwishumi elivisayo omncinci, utatomkhulu wakhe amthandayo waqalisa isifo sika-Alzheimer, esasitshisa ukuthanda kwakhe ixesha elide ukuqonda ingqondo, nokufundisa abanye ngesifo noko kunokwenziwa.

"Umsebenzi wam ugxile kakhulu ekwenzeni izisombululo zabantu ukuze baphumeze ukusebenza kwengqondo efanelekileyo," ucacisile uGupta kwi "The future Brain" kwi Psychology Today. "Nangona kunjalo, kubalulekile ukuba uqaphele ukuba ngaphambili uphando lwezonyango aluzinanzi iingqondo zabafazi kunye nemingcipheko yabasetyhini eyahlukileyo. Izibonelelo zophando ze-WAM ezinikwe oososayensi abaphezulu kunye noogqirha kwezempilo yengqondo kunye nokuthintela i-Alzheimer zinamandla okutshintsha le nyani kubuchopho babasetyhini. ”

Izibonelelo zibandakanya izazinzulu ezivela kulo lonke elaseMelika kwinqanaba lokuphanda ukuba kutheni isifo i-Alzheimer sichaphazela abasetyhini ngokungalinganiyo.

U-Lisa Mosconi, Ph.D., kwi-Initiative Health Initiative yabasetyhini e-Weill Cornell eNew York, uzakusebenzisa isibonelelo sakhe ukuphanda ukuba zeziphi ezinye izinto zokuzala (ulawulo lokuzalwa, inani lokukhulelwa, ukusetyenziswa kwehomoni kunyango, ubudala xa usexesheni, ubudala Ukuyeka ukuya exesheni) kudlala indima ekuqaleni nasekuqhubekeni kwe-Alzheimer kubafazi. Oku kwakhela phezu kwesiseko somsebenzi wakhe kwi-estrogen kunye nokuyeka ukuya exesheni njengezinto ezinobungozi be-Alzheimer's.

U-Laura Cox, Ph.D., kwiziko lika-Ann Romney leZifo ze-Neurological eBrigham nakwisibhedlele sabasetyhini eBoston, uzakusebenzisa isibonelelo sakhe ukuqonda indlela i-gut microbiota elawula ngayo i-Alzheimer ngokumodareyitha i-epigenetics emadodeni ngokuchasene nabasetyhini ukuze bafumane iindlela ukunyanga ngcono i-AD kwabasetyhini.

URoberta Diaz Brinton, Ph.D., kwiYunivesithi yaseArizona Centre for Innovation kwiBrain Science, usebenzisa isibonelelo sakhe ukufundisisa ngohlobo lwesibini lwesifo seswekile kunye nomngcipheko onxulumene ne-Alzheimer's kwabasetyhini.

UDean Ornish, MD, kwiZiko loPhando ngeMicrosoft eSan Francisco, wanikwa isibonelelo sokuqhubeka nomsebenzi wakhe wokuba nguvulindlela ekubuyiseni isifo sentliziyo ngokutshintsha indlela yokuphila ngokusebenzisa ulingo olulawulwa ngokungenamkhethe ukubona ukuba ukuqhubela phambili kwesifo i-Alzheimer's kwangoko kungaguqulwa ngendlela yokuphila iyeza.

URichard Isaacson, MD, kwiKlinikhi yokuThintela i-Alzheimer's e-Weill Cornell eNew York, uza kusebenzisa inkxaso-mali ukumisela ulwazi phakathi kwabafazi besizwe ekuqondeni kwabo isifo se-Alzheimer kunye nemingcipheko ukuze benze isikhokelo semfundo esijolise kwabasetyhini abavela kwimvelaphi eyahlukeneyo ngokusebenzisana noGqirha Eseoasa Ighodaro ovela kwikliniki yaseMayo eRochester, uGqirha uJosefina Melenze-Cabrero eSan Juan, ePuerto Rico, uGqirha Amanda Smith kwiYunivesithi yase-Southern Florida Alzheimer's Institute, kunye noGqirha Juan Melendez eJersey, eNgilane.

Inkxaso mali ibandakanya oososayensi ababhinqileyo abadibene noMbutho we-Alzheimer omsebenzi wawo waphazanyiswa sisifo se-COVID-19 sehlabathi. UMegan Zuelsdorff, Ph.D., ufunda uxinzelelo kunye nemeko yezentlalo njengezinto ezinokubangela umngcipheko;

U-Ashley Sanderlin, Ph.D., uphonononga ukutya kwe ketogenic kunye nokulala; UFayron Epps, Ph.D., uphanda ngendima yokholo kunye nokhathalelo kuluntu lwaseAfrika lwaseMelika; kunye noKendra Ray, Ph.D., baphanda ngonyango lomculo kunye nokunakekelwa.

“Ngokwembali uphando lwezamayeza luye lwabashiya ngaphandle abafazi kwiimvavanyo zeklinikhi nakwizifundo eziphambili zempilo yengqondo, nesiphumo esibuhlungu sokuba kukho umsantsa kulwazi malunga nempilo yamanina nokuba kutheni besemngciphekweni omkhulu wokuba nesifo i-Alzheimer's, isifo sengqondo esixhalabisayo kunye nezinye izifo zengqondo. , ”Utshilo uShriver. "Ukuxhasa ngezimali ngezi zifundo ze-Alzheimer's ezenzelwe abantu basetyhini kuyanceda ukuvala umsantsa. I-WAM ikholelwa ngokuqinileyo kumandla ophando, kwaye kuphela ngokuxhasa inzululwazi apho siza kuphuhlisa amanyathelo anokukhokelela kugonyo, unyango okanye unyango."

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